From: tomhoutx Newsgroups: alt.drugs.hard Subject: Re: Tussionex, was Vicodin question Date: Sat, 04 Apr 1998 15:12:46 -0600 (ROXANOL) wrote: > Tussionex doesn't have any tylenol in it, therefore it's easier to take a > higher dose with it than with Vicodin. It is also a time-release formula(kinda > good kinda bad), and has a antihistamine in it (chlorpheneramine). > > I don't know why you thought it canceled out? It's never happened to me.. > > -Roxanol > > TUSSIONEX has gone through some changes over the last several years. After being manufactured by Strasenburgh for many years which later became Penwalt, it was sold to a company that I thought was called Psion but I can't find any thing to back me up on that company name. I do know that it is now being manufactured by a London based pharmaceutical company called Medeva. It is still made in the US at their plant in Rochester NY. Tussionex has a special form of hydrocodone that is refered to as "Resin Complexes of Hydrocodone" which is a cationic exchange resin complex that causes it to metabolize slower and thus stays active in the blood for 8 to 12 hours as compared to about 4 hrs. for plain hydrocodone. There has been a change in the formulaton though. Chlorphenarimine (Chlor-Trimeton) has been substituted for Phenyltoloxamine which are both antihistamines but is the potentiate in the resignate. Although I use to sample the thick golden liquid quite often I have not tested it since it has been reformulated. I have had people tell me that it is not as strong as it use to be. You could drink 4 oz.of the stuff and have a kick ass nod for at least 6 hours. I'm curious if anyone out there has any opinions on this? I might add that Medeva reports that they have doubled the sales of Tussionex in the US in '97. That surprizes me because whenever I have mentioned that stuff to a doctor in the past couple of years they say "oh no, that stuff is too hot to write for." Maybe they are all hot scripts. Anyway, this is a quote from their web page: "With 185 sales people operating in 12 regional business units, our salesforce is of an appropriate size to support our highly targeted niche marketing strategy and its positive impact is becoming increasingly evident with promising growth in prescriptions written for Tussionex. Tussionex, the unique 12 hour anti-tussive, achieved sales of £19.5m (British Pounds) compared with £10.4m in the second half of 1996. In response to marketing efforts the product is gaining market share and in the second half of 1997 prescriptions written were 3% ahead of those for the same period in 1996, despite a 7% decline in the market sector." THAT'S A LOT OF TUSSY!