From: (Peter McDermott) Subject: Re: Dimenhydrinate/meclizine hydrochloride. Date: 1995/07/28 newsgroups: alt.drugs,alt.drugs.hard,rec.drugs.misc > Does anyone have any infomation regarding the recreational uses of the >two drugs Dimenhydrinate & Meclizine hydrochloride ?. They are commonly >found in motion sickness pills. > P.S please also add cyclizine hydrocloride to the above mentioned. I'm familiar with the recreational use of cyclizine hydrochloride. During the late 70's and 80's, the most popular opiate in the UK was a drug called Diconal, a combination of 10mg dipipanone hydrochloride, 30mg cyclizine hydrochloride. The reason it was so popular was that the dipipanone was a strong opiate, stronger than heroin, but it's strength was potentiated by the addition of the cyclizine, which produced a rush that many people preferred to heroin. The problem with this combo was that it was usually injected intravenously, and caused serious problems with venal thrombosis and abscesses. The intensity of the rush made it a very compulsive drug, and large numbers of people overdosed and died. Finally, it also caused problems by producing epileptic fits in users who had never experience fitting before, usually immediately after use, but once someone had suffered them, they could come at any time afterwards. In the late eighties, misuse of Diconal became so problematic that the Home Office rescheduled the drug, and gave it the same status as heroin and cocaine, so now it can only be prescribed to an addict by a doctor with a special licence from the Home Office. This had the impact of taking most of the Diconal off the streets, but it led afficionados to create a kind of 'do-it-yourself diconal' using either methadone ampoules or heroin and marzine tablets (which were available over the counter as travel sickness pills). Although not quite as enjoyable as Diconal, many users found this combination equally compulsive, and they were able to stretch out the opiate by using a higher ratio of marzine to opiate. Of course, the combination was similarly destructive, and so eventually, British pharmacists voluntarily agreed to stop selling the drug over the counter, and now it is only available by prescription in the USA. As a consequence, recreational use has pretty much died out over here.