From: Samson Newsgroups: alt.drugs.hard Subject: Salt shots (was Re: Heroin overdose/Speed antidote? Date: Sat, 10 Feb 2001 "annakeynow" wrote: > I dunno much about speed for opiate o.d. but, I have seen and > heard of ppl having a 'salt shot', which is just what it > sounds like. Cant recall the ratio of salt to water, and two > medical publications with articles on overdose denied it would > work. Of course they didn;'t back this up with any > statistics, facts or figures, but, well they're doctors, they > know it all. > > Seriously though, I walked into a scene once where someone was > going a nice sapphire colour around the mouth when his girlfriend > finished having her ping, not panicking at all, she made up a saline > solution, as much as would go into the 'outfit', about 3ml, and sent > it home to her boyfriend. Within a matter of 1-2 seconds, with > a lot of extra encouragement such as yelling, shaking, cold water > etc., he came 'round. [...] > Anyone else heard of saline as an antidote for o.d.? Educated folk medicine: Solomon Snyder in _Drugs and the Brain_: "When Pert, Pasternak and I examined the effect of sodium upon the binding affinity of a variety compounds, we found that opiates fell along a continuum. *Pure opiate agonists bound more weakly in the presence of sodium.* Pure opiate antagonists were not affected at all. Drugs known to have mixtures of [...] effects were influenced to an intermediate extent. Thus monitoring the effects of sodium on opiate-receptor binding provided an efficient means of screening potential mixed agonist-antagonist opiates. One could evaluate fifty drugs in half a day." (my emphasis) Yes, sodium reliably inhibits the effects of opiate agonists... in a test tube. It may work (in massive amounts) in a blue human, but it hasn't been studied for that. Just a cheap way for drug companies to screen new compounds for opiate activity, assembly-line style, _in vitro_, without even having to risk a rat's life. Again, maybe it's worked on occasion. Maybe it just *seemed* to work (post hoc ergo propter hoc). A little knowledge can be a dangerous thing...